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Biomed Opt Express. 2011 Dec 1;2(12):3284-94. doi: 10.1364/BOE.2.003284. Epub 2011 Nov 9.

Modeling diffuse reflectance from homogeneous semi-infinite turbid media for biological tissue applications: a Monte Carlo study.

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1
Department of Materials Science and Engineering, University of Ioannina, 45110 Ioannina, Greece.

Abstract

Diffuse reflectance spectroscopy is one of the simplest and widely used techniques for the non-invasive study of biological tissues but no exact analytical solution exists for the problem of diffuse reflectance from turbid media such as biological tissues. In this work, a general treatment of the problem of diffuse reflectance from a homogeneous semi-infinite turbid medium is presented using Monte Carlo simulations. Based on the results of the Monte Carlo method, simple semi-empirical analytical solutions are developed valid for a wide range of collection geometries corresponding to various optical detector diameters. This approach may be useful for the quick and accurate modeling of diffuse reflectance from tissues.

KEYWORDS:

(170.3660) Light propagation in tissues; (170.6510) Spectroscopy, tissue diagnostics; (170.7050) Turbid media

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