Format

Send to

Choose Destination
See comment in PubMed Commons below
Clin Nutr. 2012 Apr;31(2):156-67. doi: 10.1016/j.clnu.2011.11.011. Epub 2011 Dec 10.

Comparison of aerobic exercise, diet or both on lipids and lipoproteins in adults: a meta-analysis of randomized controlled trials.

Author information

1
Department of Community Medicine, West Virginia University, Morgantown, WV 26506-9190, United States. gkelley@hsc.wvu.edu

Abstract

OBJECTIVE:

Given that previous studies have reached conflicting conclusions regarding the effects of diet (D), aerobic exercise (E) or both (DE) on blood lipid and lipoprotein concentrations in adults, the meta-analytic approach was used to address this issue.

DATA SOURCES:

Nine electronic databases, cross-referencing, and expert review.

STUDY SELECTION:

Randomized controlled trials ≥ 4 weeks that included a D, E, DE and control (C) group in adults ≥ 18 years of age and in which data for one or more of the following were available: total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG).

DATA EXTRACTION:

Dual data extraction by the first two authors.

STATISTICAL ANALYSIS:

Random-effects models as well as mixed-effects models for between-group differences.

RESULTS:

Seven-hundred and eighty-eight men and women from 6 studies were included. Non-overlapping 95% confidence intervals were observed for D and DE with respect to lowering TC, LDL-C and TG while reductions in E were limited to TG. No significant changes in HDL-C were observed. When compared to E, reductions in TC and LDL-C were greater for D and DE (p < 0.05 for all).

CONCLUSIONS:

Diet, especially DE, are superior to E for improving selected lipids and lipoproteins in adults.

PMID:
22154987
PMCID:
PMC3311746
DOI:
10.1016/j.clnu.2011.11.011
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Support Center