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Curr Opin Biotechnol. 2012 Feb;23(1):9-15. doi: 10.1016/j.copbio.2011.11.013. Epub 2011 Dec 9.

Next generation sequencing and bioinformatic bottlenecks: the current state of metagenomic data analysis.

Author information

1
Genome Science Group, Los Alamos National Laboratory, Los Alamos, NM 87545, United States.

Abstract

The recent technological advances in next generation sequencing have brought the field closer to the goal of reconstructing all genomes within a community by presenting high throughput sequencing at much lower costs. While these next-generation sequencing technologies have allowed a massive increase in available raw sequence data, there are a number of new informatics challenges and difficulties that must be addressed to improve the current state, and fulfill the promise of, metagenomics.

PMID:
22154470
DOI:
10.1016/j.copbio.2011.11.013
[Indexed for MEDLINE]

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