Hand injuries are a common complaint in the emergency department (ED). Oftentimes, these injuries occur in work settings. We report a case of a healthy EMS provider presenting to the ED with a left thumb injury that turned out to be an isolated trapezium subluxation.Using bedside fluoroscopy, the thumb carpometacarpal joint was isolated, injected, and subsequently reduced. The clinical course and management are discussed as well as a brief review of hand injuries.