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J AAPOS. 2011 Dec;15(6):545-50. doi: 10.1016/j.jaapos.2011.07.008.

Changes in binocular function in anisometropic nonstrabismic children with optical correction and occlusion therapy.

Author information

1
Cairo University Faculty of Medicine, Cairo, Egypt. ahmedawadein@yahoo.com

Abstract

PURPOSE:

To identify factors that influence binocular function in anisometropic, nonstrabismic children before and after optical correction and amblyopia therapy.

METHODS:

This was a prospective observational study of consecutive patients with nonstrabismic anisometropia. Visual acuity and responses to the 4(Δ) base-out prism test, the Worth 4-dot test, and the TNO test were recorded after spectacle correction and every 3 months for 1 year. Factors affecting visual acuity and binocular function were analyzed using univariate and multiple stepwise regression analysis.

RESULTS:

A total of 118 subjects were enrolled. At the end of the first year, the mean improvement in visual acuity was 2.6 ± 2.3 lines. The percentage of patients showing a positive response to the 4(Δ) base-out prism test increased from 47% to 79%; fusion in the Worth 4-dot test, from 37% to 66%; and measurable stereopsis on TNO testing, from 59% to 80%. Better initial visual acuity and better final visual acuity were associated with better binocular function. Interocular refractive error difference was a predictor of poor binocular function in multiple regression analysis if the difference in spherical error exceeded 4 D. Patients with amblyopia showed significantly worse binocular function compared to those with no amblyopia.

CONCLUSIONS:

Binocular function of anisometropic children can be improved with refractive correction and amblyopia therapy.

PMID:
22153398
DOI:
10.1016/j.jaapos.2011.07.008
[Indexed for MEDLINE]

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