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Metab Syndr Relat Disord. 2012 Apr;10(2):128-36. doi: 10.1089/met.2011.0064. Epub 2011 Dec 13.

General versus central adiposity and relationship to pediatric metabolic risk.

Author information

1
USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas, USA. jason.mendoza@bcm.edu

Abstract

BACKGROUND:

The influence of moderate-to-vigorous physical activity (MVPA) and general versus central adiposity on pediatric metabolic risk is not well described.

METHODS:

Secondary analyses on pediatric participants from the National Health and Nutrition Examination Survey, 2003-2006 (n=2,155). MVPA (min/day) and adherence to MVPA recommendations were assessed objectively by accelerometers. Body mass index (BMI) z-score and waist circumference (WC) were measured by standard protocols. The main dependent variables included an overall metabolic risk score and clinical tests related to metabolic risk. A series of linear regression analyses were used to examine BMI z-score versus WC as a mediator of the relationship between MVPA and the metabolic risk score or the individual components, controlling for sociodemographic covariates. All analyses with BMI z-score as an independent variable controlled for WC and vice versa. The product-of-coefficients method was used to test for mediation.

RESULTS:

MVPA adherence was inversely associated and WC was positively associated with the metabolic risk score (all P<0.05). MVPA was inversely associated with systolic blood pressure and positively associated with high-density lipoprotein cholesterol (HDL-C) (all P<0.05). WC was inversely associated with HDL-C and positively associated with C-reactive protein (CRP), glycohemoglobin, fasting triglycerides, and fasting insulin (all P<0.05). WC mediated the relationship between MVPA and CRP or HDL-C (both P<0.05).

CONCLUSIONS:

MVPA correlated with pediatric metabolic risk and this relationship was mediated by central adiposity for CRP and HDL-C. This finding suggests the need for programs to screen for and improve children's MVPA and WC.

PMID:
22149935
PMCID:
PMC3339386
DOI:
10.1089/met.2011.0064
[Indexed for MEDLINE]
Free PMC Article

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