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J Nat Prod. 2012 Jan 27;75(1):98-102. doi: 10.1021/np200493t. Epub 2011 Dec 12.

Dihydroagarofuran derivatives from the dried roots of Tripterygium wilfordii.

Author information

1
Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, People's Republic of China.

Abstract

Five new sesquiterpene derivatives, including dihydroagarofuran pyridine macrolides 1-4 and dihydroagarofuran ester 18, and 13 known dihydroagarofuran derivatives were isolated from the aqueous EtOH extract of the dried roots of Tripterygium wilfordii. An in vitro antiherpetic activity assay indicated that compounds 11 and 17 displayed weak and moderate inhibition against herpes simplex virus type II, respectively.

PMID:
22148431
DOI:
10.1021/np200493t
[Indexed for MEDLINE]

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