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Zh Vyssh Nerv Deiat Im I P Pavlova. 2011 Sep-Oct;61(5):624-30.

[Behavioral characteristics of female Wag/Rij rats].

[Article in Russian]

Abstract

Behavior of male and female WAG/Rij and Wistar rats was compared in the tests assessing the level of anxiety (light-dark choice, open field) and depression-like state (sucrose intake and preference, forced swimming). Females of WAG/Rij rats like males of the same strain exhibited symptoms of depression-like behavior: increased immobility in the forced swimming test and decreased sucrose intake and preference (anhedonia). In contrast to males, females of WAG/Rij rats displayed more distinct signs of increased anxiety as compared to Wistar rats. Both WAG/Rij and Wistar females exhibited increased locomotor and exploratory activity in the open field as compared to males.

PMID:
22145338
[Indexed for MEDLINE]

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