Format

Send to

Choose Destination
See comment in PubMed Commons below
Indian J Endocrinol Metab. 2011 Oct;15 Suppl 4:S317-21. doi: 10.4103/2230-8210.86974.

Cushing's syndrome: Stepwise approach to diagnosis.

Author information

  • 1Department of Endocrinology, Seth G. S. Medical College, Parel, Mumbai, Maharashtra, India.

Abstract

The projected prevalence of Cushing's syndrome (CS) inclusive of subclinical cases in the adult population ranges from 0.2-2% and it may no longer be considered as an orphan disease (2-3 cases/million/year). The recognition of CS by physicians is important for early diagnosis and treatment. Late-night salivary cortisol, dexamethasone suppressiontesti, or 24-h urine free cortisol are good screening tests. Positively screened cases need stepwise evaluation by an endocrinologist. This paper discusses the importance of screening for CS and suggests a stepwise diagnostic approach to a case of suspected hypercortisolism.

KEYWORDS:

Cushing's syndrome; dexamethasone suppression tests; hypercortisolism; salivary cortisol; urinary free cortisol

PMID:
22145134
PMCID:
PMC3230095
DOI:
10.4103/2230-8210.86974
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Medknow Publications and Media Pvt Ltd Icon for PubMed Central
    Loading ...
    Support Center