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Angew Chem Int Ed Engl. 2011 Dec 23;50(52):12406-10. doi: 10.1002/anie.201106707. Epub 2011 Dec 5.

Decoding genomes at high speed: implications for science and medicine.

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1
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. sb10031@cam.ac.uk

Abstract

At warp speed: The speed and cost of sequencing DNA has undergone tremendous improvement based on Solexa sequencing. This technique arose from basic curiosity-driven research and unexpected outcomes, rather than from ideas that were strategically driven. The whole-genome sequencing of individuals now possible may one day transform the way medical disorders are classified, diagnosed, and treated.

PMID:
22144295
DOI:
10.1002/anie.201106707
[Indexed for MEDLINE]
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