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Curr Allergy Asthma Rep. 2012 Feb;12(1):79-84. doi: 10.1007/s11882-011-0239-y.

Management of multiple drug allergies in children.

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Children's Hospital Boston, Division of Immunology, Harvard Medical School, Boston, MA 02115, USA.


Children with multiple drug allergies are likely to require treatment with one or more of the drugs to which they may have had a reaction, when there is no alternate effective drug available. Detailed review of their history and/or use of appropriate diagnostic studies will help determine the potential safety of readministering the desired drug as well as the method for its readministration, most likely in the form of a drug challenge or desensitization. A practical approach to the diagnosis and treatment of children with multiple drug allergies is described in this review.

[Indexed for MEDLINE]

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