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J Rheumatol. 1990 Aug;17(8):1087-90.

Pulmonary-renal syndrome with "triad" involvement due to small vessel vasculitis.

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Department of Medicine, University of Iowa College of Medicine, Iowa City 52242.


We describe the clinical course and morphologic findings of a 22-year-old woman presenting with a systemic disease that included nasal ulceration, hemoptysis and rapidly progressive renal failure. Biopsies of nasal septum and lung revealed small vessel leukocytoclastic angiitis while renal biopsy showed a diffuse crescentic glomerulonephritis. Immunosuppressive therapy resulted in remission of clinical symptoms and resolution of glomerulonephritis as documented in a followup biopsy. Although her clinical presentation with triad organ involvement strongly suggested Wegener's granulomatosis, this case illustrates that other varieties of vasculitis may mimic Wegener's granulomatosis.

[Indexed for MEDLINE]

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