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Can Assoc Radiol J. 2012 Nov;63(4):289-93. doi: 10.1016/j.carj.2011.04.003. Epub 2011 Dec 3.

Thyroid incidentalomas on fluorine-18-fluorodeoxyglucose positron emission tomography-computed tomography: incidence, malignancy risk, and comparison of standardized uptake values.

Author information

1
Department of Nuclear Medicine and PET, Singapore General Hospital, Singapore. kao.yung.hsiang@singhealth.com.sg

Abstract

INTRODUCTION:

To determine the incidence of fluorine-18-fluorodeoxyglucose (FDG) avid thyroid incidentalomas detected on positron emission tomography (PET) with integrated computed tomography (CT), and correlate the FDG-PET-CT findings to cytology.

METHODS:

A total of 942 FDG-PET-CT reports were retrospectively reviewed. Patients with FDG-avid thyroid incidentalomas were further reviewed for correlative cytology.

RESULTS:

The incidence of FDG-avid thyroid incidentalomas is 2.2%. Thyroid malignancies were identified in 3 of 6 patients who underwent cytologic correlation, with a positive predictive value of 50% (95% confidence interval, 14%-86%). The mean maximum standardized uptake values of benign and malignant FDG-avid thyroid incidentalomas were 5.6 and 6.6, respectively.

CONCLUSION:

A FDG-avid thyroid incidentaloma may predict underlying malignancy. Cytologic assessment should be considered for FDG-avid thyroid incidentalomas.

PMID:
22136969
DOI:
10.1016/j.carj.2011.04.003
[Indexed for MEDLINE]
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