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Int J Med Mushrooms. 2011;13(1):27-31.

An antifungal protein from the culinary-medicinal beech mushroom, Hypsizygus marmoreus (Peck) Bigel. (Agaricomycetideae).

Author information

1
Innovation and Joint Research Center, Shizuoka University, Suruga-ku, Shizuoka, Japan.

Abstract

An antifungal protein (HM-af) was purified from the culinary-medicinal mushroom Hypsizygus marmoreus. The results of sodium dodecyl sulfate polyacrylamide gel electrophoresis and matrix-assisted laser desorption ionization time-of-flight mass spectrometry of HM-af indicated that its molecular mass was 9.5 kDa. The N-terminal amino acid sequence of HM-af showed homology to ribonuclease H from Clostridium thermocellum. HM-af showed the antifungal activity against Flammulina velutipes.

PMID:
22135901
DOI:
10.1615/intjmedmushr.v13.i1.40
[Indexed for MEDLINE]

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