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Cogn Behav Neurol. 2011 Dec;24(4):174-86. doi: 10.1097/WNN.0b013e31823f90eb.

Smooth pursuit and fixation ability in children with Tourette syndrome.

Author information

  • 1Centre for Vision Research, York University, Toronto, Ontario, Canada. dianapar@yorku.ca

Abstract

OBJECTIVE:

The smooth pursuit eye movements and fixation ability of children aged 8 to 16 years with Tourette syndrome (TS) were examined.

BACKGROUND:

Although several studies have examined the saccadic ability of patients with TS, there have been only a few studies examining pursuit ability in TS.

METHOD:

Pursuit gain (eye velocity/target velocity) and intrusive saccades during fixation were measured in children with TS-only, TS+attention deficit hyperactivity disorder (ADHD), and TS+ADHD+obsessive compulsive disorder (OCD), and in controls (8 to 16 y). Two pursuit tasks and 1 fixation task were used. In random pursuit 1 (RP1), each step and ramp cycle began from fixation; in random pursuit 2 (RP2), each cycle followed the next. In the fixation task, children were required to maintain fixation on a center dot and ignore distractor stimuli.

RESULTS:

All children had significantly higher pursuit gains in RP2 than in RP1 when pursuing a 30 degrees/s moving target. In addition, in RP2, the TS+ADHD+OCD group displayed significantly higher pursuit gains relative to the TS-only, TS+ADHD, and control groups. In the fixation task, the TS+ADHD group exhibited significantly more intrusive saccades than the TS+ADHD+OCD and control groups.

CONCLUSIONS:

Our findings support an enhanced oculomotor ability in the TS+ADHD+OCD group and the presence of an online gain control mechanism during ongoing pursuit. These findings are discussed in more detail.

PMID:
22134192
DOI:
10.1097/WNN.0b013e31823f90eb
[PubMed - indexed for MEDLINE]
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