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Nat Rev Genet. 2011 Nov 29;13(1):21-35. doi: 10.1038/nrg3094.

Emerging biomedical applications of synthetic biology.

Author information

1
Faculty of Biology, University of Freiburg, Schänzlestrasse 1, D-79104 Freiburg, Germany.

Abstract

Synthetic biology aims to create functional devices, systems and organisms with novel and useful functions on the basis of catalogued and standardized biological building blocks. Although they were initially constructed to elucidate the dynamics of simple processes, designed devices now contribute to the understanding of disease mechanisms, provide novel diagnostic tools, enable economic production of therapeutics and allow the design of novel strategies for the treatment of cancer, immune diseases and metabolic disorders, such as diabetes and gout, as well as a range of infectious diseases. In this Review, we cover the impact and potential of synthetic biology for biomedical applications.

PMID:
22124480
DOI:
10.1038/nrg3094
[Indexed for MEDLINE]

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