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RETRACTED ARTICLE

See: Retraction Notice

Curr Opin Hematol. 2012 Jan;19(1):52-7. doi: 10.1097/MOH.0b013e32834da93b.

Lithium in the treatment of neutropenia.

Author information

1
Unit of Haematology, Department of Oncology, Transplants and Advanced Technologies in Medicine, University of Pisa-AOUP, Pisa, Italy. mario.petrini@med.unipi.it

Retraction in

Abstract

PURPOSE OF REVIEW:

The capacity of lithium to induce neutrophilia and increase circulating CD34(+) cells of marrow origin has long been known. Lithium has been the object of hematological investigations for many years, but no definitive use in hematology has yet emerged.

RECENT FINDINGS:

We review the evidence that lithium increases granulocyte colony-stimulating factor (G-CSF) and augments G-CSF effects, showing its potential use in stem cell mobilization and engraftment of stem cell transplantation.

SUMMARY:

We suggest possible therapeutic uses of lithium in neutropenia. In bone marrow transplantation, preharvest lithium-assisted hematopoietic stem cell mobilization may be useful as well.

PMID:
22123660
DOI:
10.1097/MOH.0b013e32834da93b
[Indexed for MEDLINE]

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