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Int J Mol Imaging. 2011;2011:714021. doi: 10.1155/2011/714021. Epub 2011 Oct 25.

Diffusion MR Imaging of the Brain in Patients with Cancer.

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Department of Radiology, Section of Neuroradiology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, FCT16.024, Unit 1482, Houston, TX 77030, USA.


Over the last several years, there has been significant advancement in the molecular characterization of intracranial diseases, particularly cerebral neoplasms. While nuclear medicine technology, including PET/CT, has been at the foreground of exploration, new MR imaging techniques, specifically diffusion-weighted and diffusion tensor imaging, have shown interesting applications towards advancing our understanding of cancer involving the brain. In this paper, we review the fundamentals and basic physics of these techniques, and their applications to patient care for both general diagnostic use and in answering specific questions in selection of patients in terms of expected response to treatment.

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