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J Infect. 2012 Apr;64(4):347-73. doi: 10.1016/j.jinf.2011.11.014. Epub 2011 Nov 18.

Management of suspected viral encephalitis in adults--Association of British Neurologists and British Infection Association National Guidelines.

Author information

1
Institute of Infection and Global Health, University of Liverpool, The Apex Building, West Derby Street, Liverpool, UK. tsolomon@liv.ac.uk

Abstract

In the 1980s the outcome of patients with herpes simplex encephalitis was shown to be dramatically improved with aciclovir treatment. Delays in starting treatment, particularly beyond 48 h after hospital admission, are associated with a worse prognosis. Several comprehensive reviews of the investigation and management of encephalitis have been published. However, their impact on day-to day clinical practice appears to be limited. The emergency management of meningitis in children and adults was revolutionised by the introduction of a simple algorithm as part of management guidelines. In February 2008 a group of clinicians met in Liverpool to begin the development process for clinical care guidelines based around a similar simple algorithm, supported by an evidence base, whose implementation is hoped would improve the management of patients with suspected encephalitis.

PMID:
22120595
DOI:
10.1016/j.jinf.2011.11.014
[Indexed for MEDLINE]

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