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Epilepsy Res. 2012 Mar;99(1-2):180-2. doi: 10.1016/j.eplepsyres.2011.10.021. Epub 2011 Nov 25.

Low glycemic index treatment for epilepsy in tuberous sclerosis complex.

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Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, United States.


Retrospective chart review of 15 patients with tuberous sclerosis complex (TSC) who initiated the low glycemic index treatment (LGIT) for epilepsy management at Massachusetts General Hospital over a five-year period. Prior to dietary therapy, this cohort (average age: 8.5 years) had tried an average of 5.8 anti-epileptic drugs with incomplete seizure control. At 6 months on the LGIT, 7/15 (47%) patients experienced >50% reduction in seizure frequency.

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