Non-high-density lipoprotein cholesterol and its correlation with anthropometric markers of cardiovascular risk in hemodialysis

J Ren Nutr. 2012 Mar;22(2):251-257. doi: 10.1053/j.jrn.2011.08.009. Epub 2011 Nov 25.

Abstract

Introduction: Non-high-density lipoprotein cholesterol (non-HDL-c) may be a better indicator of atherogenicity in the hemodialysis population.

Purpose: To investigate the correlation of non-HDL-c with anthropometric measurements associated to cardiovascular risk, such as body mass index, waist circumference, waist-to-height ratio, waist-to-height(2) ratio, and waist-to-hip circumference ratio.

Methods: We evaluated anthropometric markers and lipids in 86 hemodialysis patients, and the correlation between them was investigated.

Results: Non-HDL-c had a positive correlation with body mass index (r = 0.273; P = .01), waist circumference (r = 0.375; P = .000), waist-to-height ratio (r = 0.333; P = .002), waist-to-height(2) ratio (r = 0.270; P = .012), and waist-to-hip circumference ratio (r = 0.356; P = .001).

Conclusions: This study detected a positive and significant correlation between non-HDL-c, but not low-density lipoprotein cholesterol, and the anthropometric cardiovascular risk indexes. We could suggest that non-HDL-c can be used as a cardiovascular risk factor indicator among dialysis patients.

MeSH terms

  • Adipose Tissue
  • Adult
  • Aged
  • Aged, 80 and over
  • Biomarkers / blood*
  • Body Composition
  • Body Mass Index
  • Brazil / epidemiology
  • Cardiovascular Diseases / blood*
  • Cardiovascular Diseases / complications
  • Cardiovascular Diseases / etiology
  • Cholesterol, HDL / blood*
  • Cholesterol, LDL / blood*
  • Dyslipidemias / complications
  • Dyslipidemias / epidemiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Renal Dialysis*
  • Risk Factors
  • Waist Circumference
  • Waist-Hip Ratio
  • Young Adult

Substances

  • Biomarkers
  • Cholesterol, HDL
  • Cholesterol, LDL