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Curr Biol. 2011 Nov 22;21(22):R916-8. doi: 10.1016/j.cub.2011.10.020.

Cellular mechanotransduction: filamin A strains to regulate motility.

Author information

1
Department of Biological Sciences, Columbia University, New York, NY, USA.

Abstract

A new study suggests that mechanical strain through the actin-binding protein filamin A leads to increased linkage between the extracellular matrix and cytoskeleton and decreased actin dynamics.

PMID:
22115457
PMCID:
PMC3396208
DOI:
10.1016/j.cub.2011.10.020
[Indexed for MEDLINE]
Free PMC Article

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