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J Antibiot (Tokyo). 1990 Sep;43(9):1082-8.

Sequence determination of actagardine, a novel lantibiotic, by homonuclear 2D NMR spectroscopy.

Author information

1
Merrell Dow Research Institute, Lepetit Research Center, Varese, Italy.

Abstract

By combination of several 1H NMR techniques, the sequence of actagardine has been elucidated. It has been shown that it is a tetracyclic 19-residue peptide antibiotic. It differs from the previously described lanthionine-containing peptide antibiotics belonging to the lantibiotic class.

PMID:
2211371
DOI:
10.7164/antibiotics.43.1082
[Indexed for MEDLINE]
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