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J Antibiot (Tokyo). 1990 Aug;43(8):920-30.

Janthinocins A, B and C, novel peptide lactone antibiotics produced by Janthinobacterium lividum. II. Structure elucidation.

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1
Squibb Institute for Medical Research, Princeton, NJ 08543-4000.

Abstract

The structures of janthinocins A, B and C, three novel macrocyclic peptide lactone antibiotics isolated from fermentations of Janthinobacterium lividum, were determined. The janthinocins are of particular interest because they contain three amino acid residues that have not previously been reported in natural products: Each contains erythro-beta-hydroxy-D-leucine while janthinocins A and B also contain beta-hydroxytryptophan and beta-ketotryptophan, respectively.

PMID:
2211360
DOI:
10.7164/antibiotics.43.920
[Indexed for MEDLINE]
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