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Rehabil Res Pract. 2010;2010:481546. doi: 10.1155/2010/481546. Epub 2010 Aug 5.

Endurance and Resistance Training in Radically Treated Respiratory Cancer patients: A Pilot Study.

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Department of Respiratory Medicine, Faculty of Medicine and Health Sciences, Ghent University Hospital, De Pintelaan 185, 7K12IE B-9000 Ghent, Belgium.



Respiratory cancer and its treatment are known to contribute to muscle weakness and functional impairment.


To assess the effects of rehabilitation in patients with respiratory cancer.


Radically treated respiratory cancer patients were included in a 12-week multidisciplinary rehabilitation program.


16 patients (age: 61 ± 7 years; FEV(1): 57 ± 16% pred.) showed a reduced exercise tolerance (VO(2)max: 56 ± 15% pred.; 6 MWD: 67 ± 11% pred.), muscle force (PImax: 54 ± 22% pred.; QF: 67 ± 16% pred.), and quality of life (CRDQd: 17 ± 5 points; CRDQf: 16 ± 5 points). Exercise tolerance, muscle force, and quality of life improved significantly after rehabilitation.


Radically treated patients with respiratory cancer have a decreased exercise capacity, muscle force, and quality of life. 12 weeks of rehabilitation leads to a significant improvement in exercise capacity, respiratory muscle force, and quality of life.

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