Format

Send to

Choose Destination
Dermatoendocrinol. 2011 Jul;3(3):211-5. doi: 10.4161/derm.3.3.17027. Epub 2011 Jul 1.

Thyroid hormone action on skin.

Author information

1
Associate Professor of Medicine and Molecular Medicine; Section of Endocrinology, Diabetes and Nutrition; Boston University School of Medicine; Boston, MA USA.

Abstract

The skin characteristics associated with thyroid hormone are classic. The name "myxedema" refers to the associated skin condition caused by increased glycosaminoglycan deposition in the skin. Generalized myxedema is still the classic cutaneous sign of hypothyroidism. It is caused by deposition of dermal acid mucopolysaccharides, notably hyaluronic acid. Despite its appearance, the skin does not pit with pressure.

KEYWORDS:

cutaneous; dermis; epidermis; skin; thyroid hormone

Supplemental Content

Full text links

Icon for Taylor & Francis Icon for PubMed Central
Loading ...
Support Center