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J Exp Med. 2011 Nov 21;208(12):2351-5. doi: 10.1084/jem.20112160.

100 years of Rous sarcoma virus.

Author information

1
Division of Infection and Immunity, University College London, WC1E 6BT, England, UK. r.weiss@ucl.ac.uk

Abstract

The discovery of Rous sarcoma virus, which was reported by Peyton Rous in the Journal of Experimental Medicine 100 years ago, opened the field of tumor virology. It showed that some cancers have infectious etiology, led to the discovery of oncogenes, and laid the foundation for the molecular mechanisms of carcinogenesis. Rous spent his entire research career at The Rockefeller Institute, and he was the JEM's longest serving editor. Here, we comment briefly on the life of this remarkable scientist and on the importance of his discoveries.

PMID:
22110182
PMCID:
PMC3256973
DOI:
10.1084/jem.20112160
[Indexed for MEDLINE]
Free PMC Article
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