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Nucleic Acids Res. 2012 Jan;40(Database issue):D790-6. doi: 10.1093/nar/gkr1046. Epub 2011 Nov 18.

SABIO-RK--database for biochemical reaction kinetics.

Author information

1
Scientific Databases and Visualization Group, Heidelberg Institute for Theoretical Studies, gGmbH, Schloss-Wolfsbrunnenweg 35, 69118 Heidelberg, Germany. Ulrike.Wittig@h-its.org

Abstract

SABIO-RK (http://sabio.h-its.org/) is a web-accessible database storing comprehensive information about biochemical reactions and their kinetic properties. SABIO-RK offers standardized data manually extracted from the literature and data directly submitted from lab experiments. The database content includes kinetic parameters in relation to biochemical reactions and their biological sources with no restriction on any particular set of organisms. Additionally, kinetic rate laws and corresponding equations as well as experimental conditions are represented. All the data are manually curated and annotated by biological experts, supported by automated consistency checks. SABIO-RK can be accessed via web-based user interfaces or automatically via web services that allow direct data access by other tools. Both interfaces support the export of the data together with its annotations in SBML (Systems Biology Markup Language), e.g. for import in modelling tools.

PMID:
22102587
PMCID:
PMC3245076
DOI:
10.1093/nar/gkr1046
[Indexed for MEDLINE]
Free PMC Article

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