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Vet Microbiol. 2012 Apr 23;156(1-2):217-21. doi: 10.1016/j.vetmic.2011.10.023. Epub 2011 Nov 3.

Detection of bacterial DNA in bile of cats with lymphocytic cholangitis.

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1
Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands. cmaotte@hotmail.com

Abstract

In this study, we have successfully used molecular methods based on the amplification of the 16S ribosomal RNA gene on feline bile samples to show that bile of cats with LC is not sterile. This is probably due to the fact that the inflammatory process in the biliary tree causes dilatations. As a result, bacteria can easily migrate from the intestines via the common bile duct. The diversity of species identified and the presence of Helicobacter spp. DNA in both patients and controls suggests that bacteriobilia is secondary to the disease and is not the cause of LC.

PMID:
22101090
DOI:
10.1016/j.vetmic.2011.10.023
[Indexed for MEDLINE]
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