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Gynecol Obstet Fertil. 2012 Feb;40(2):99-103. doi: 10.1016/j.gyobfe.2011.08.026. Epub 2011 Nov 17.

[Flow Index Vascularization dynamics in the preovulatory phase of controlled ovarian hyperstimulation: profile and relationship with conception rate].

[Article in French]

Author information

1
Laboratoire d’Eylau, 55, rue Saint-Didier, 75116 Paris, France. philippe@vignal.org

Abstract

OBJECTIVES:

To study the evolution of subendometrial vascularization flow index (VFI) in controlled ovarian hyperstimulation (COH+IIU) cycles and compare its dynamic changes in pregnant and non pregnant women.

PATIENTS AND METHODS:

This is a retrospective study on 61 couples. To determine the profile of IVF just before ovulation, patients had 3D-Power Doppler angiography (3D-PDA) in this precise preovulatory phase.

RESULTS:

We observed a decreasing profile of VFI in 52% (32/61) of the main group cycles, in 45% (14/31) of the subgroup with spontaneous peak of LH (luteinizing hormone), and in 60% (18/30) of the hCG (human chorionic gonadotropin) trigger subgroup. There were ten conceptions, (10/61, 16.4%), including eight (8/32, 30%) that were associated with a decreasing profile of VFI versus two (2/29, 7%) that were associated with an increasing profile (NS). In the detection of LH peak subgroup, we observed five conceptions (5/14, 36%) associated with a decreasing profile versus one conception (1/17, 6%) associated with an increasing profile of VFI (OR: 8.3; confidence interval [CI] 95%: 0.8-444; P=0.06 in favor of a of decreasing VFI profile). In the hCG subgroup, there were three conceptions in the decreasing VFI profile (3/18, 17%) and one conception with increasing VFI (1/12, 17%, P=0.6).

DISCUSSION AND CONCLUSION:

In controlled ovarian hyperstimulation, a decreasing VFI profile is more common compared to an increasing one. Such au profile seems to be associated with a higher conception rate in cycles with spontaneous LH surge.

PMID:
22099977
DOI:
10.1016/j.gyobfe.2011.08.026
[Indexed for MEDLINE]

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