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J Nat Sci Biol Med. 2010 Jul;1(1):12-5. doi: 10.4103/0976-9668.71666.

Antibacterial activity of garlic extract on streptomycin-resistant Staphylococcus aureus and Escherichia coli solely and in synergism with streptomycin.

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1
Aditya Institute of Pharmaceutical Sciences and Research, A.D.B. Road, Aditya Nagar, Surampalem, East Godavari District, Andhra Pradesh, India.

Abstract

This study focuses the significant antibacterial activity of Garlic (Allium sativum Linn.) extract on streptomycin-resistant strains solely and in synergism with streptomycin. Gram-positive Staphylococcus aureus ATCC BAA 1026 and gram-negative Escherichia coli ATCC 10536 were made resistant to standard antibiotic streptomycin used as a control in the experiment. Zones of inhibition of different treatment groups were measured by agar-well-diffusion assay and compared with control. Statistical comparison of sole extract and streptomycin synergism with streptomycin control had proved it significant.

KEYWORDS:

Antibacterial; Escherichia coli; Staphylococcus aureus; antibiotic; resistance; synergism

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