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Hepat Mon. 2011 May;11(5):346-50.

The prevalence of hepatitis B antigen-positivity in the general population of Mashhad, Iran.

Author information

1
Research Center for HIV/AIDS, HTLV and Viral Hepatitis, Iranian Academic Center for Education, Culture and Research (ACECR), Mashhad Branch, Mashhad, IR Iran.

Abstract

BACKGROUND:

Hepatitis B virus (HBV) infection is a significant health problem throughout the world.

OBJECTIVES:

We aimed to evaluate the prevalence of hepatitis B antigen (HBsAg) seropositivity in the general population of Mashhad, northeast of Iran.

PATIENTS AND METHODS:

One thousand six hundred fifty-two healthy individuals aged 1 to 90 (Mean; 29.1 ± 18.5) from all 12 municipalities of Mashad were selected randomly by multistage cluster sampling. Informed consent was obtained, and demographics and medical histories were collected. Twice-reactive samples were considered HBsAg-positive by ELISA. Chi-square test and logistic regression were applied to analyze the factors related to HBsAg positivity using SPSS 16.0.

RESULTS:

The overall prevalence of HBsAg positivity was 1.39% (95% CI, 0.91% to 2.12%); 2.0% and 0.89% among men and women, respectively (p = 0.054). Infection was more prevalent in older (p = 0.019) and married persons (p = 0.001), Afghanis (p = 0.046), and those with a history of traditional cupping (p = 0.005). There was no association between HBV infection and gender; literacy; income; employment; family size; or history of blood transfusion, dental procedure, surgery, hospitalization, or tattooing. By logistic regression analysis, age was the only variable that had a significant association with infection (p = 0.026).

CONCLUSION:

It seems that the prevalence of HBV infection in Mashhad is slightly lower than that of the nation.

KEYWORDS:

HBsAg; Hepatitis B virus; Iran; Population group; Risk factor

PMID:
22087159
PMCID:
PMC3212777

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