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Chem Phys Lipids. 1990 Jul;55(1):25-8.

Severe hypoxia activates lipid peroxidation in the rat brain.

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A.A. Bogomoletz Institute of Physiology, Academy of Sciences of the Ukrainian SSR, Kiev.


The level of lipid peroxides, concentration of lactic acid in the blood and brain tissue homogenates were measured in rats under hypoxic hypoxia and hemorrhage. Significant correlation was found between the O2 supply-consumption ratio, the concentration of lactate and the level of lipid peroxides. It is suggested that the peroxidation process is activated by hypoxia.

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