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Kidney Int. 2011 Dec;80(11):1117-9. doi: 10.1038/ki.2011.298.

Old friends form alliance against podocytes.

Author information

1
Center for Systems Biology, ZBSA, Albert Ludwig University of Freiburg, Freiburg, Germany. matias.simons@uniklinik-freiburg.de

Abstract

Wang and colleagues identify the activation of Wnt signaling as an important downstream event in transforming growth factor-β-mediated podocyte injury. Supported by other recent studies, canonical Wnt signaling is emerging as a critical stress pathway in podocytes and may be exploited for therapeutic strategies in the treatment of glomerulopathies.

PMID:
22083635
DOI:
10.1038/ki.2011.298
[Indexed for MEDLINE]
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