Zinc-replacement therapy may not reduce oral pain in patients with zinc-deficient burning mouth syndrome (BMS)

Vinodh Bhoopathi; Ana Karina Mascarenhas

doi:10.1016/j.jebdp.2011.09.016

Zinc-replacement therapy may not reduce oral pain in patients with zinc-deficient burning mouth syndrome (BMS)

J Evid Based Dent Pract. 2011 Dec;11(4):189-90. doi: 10.1016/j.jebdp.2011.09.016.

Authors

Vinodh Bhoopathi¹, Ana Karina Mascarenhas

Affiliation

¹ Nova Southeastern University College of Dental Medicine, Fort Lauderdale, FL 33328, USA. Vinodh.Bhoopathi@nova.edu

PMID: 22078830
DOI: 10.1016/j.jebdp.2011.09.016

Abstract

Article title and bibliographic information: Zinc deficiency may be a cause of burning mouth syndrome as zinc replacement therapy has therapeutic effects. Cho GS, Han MW, Lee B, Roh J, Choi S, Cho K, et al. J Oral Pathol Med 2010;39(9):722-7.

Reviewers: Vinodh Bhoopathi, BDS, MPH, DScD, Ana Karina Mascarenhas, BDS, MPH, DrPH PURPOSE/QUESTION: In patients with BMS and low serum zinc levels, does zinc-replacement therapy reduce pain? Authors using an animal model also attempted to demonstrate a causal relationship between BMS and zinc deficiency

Source of funding: Information not available

Type of study/design: Randomized controlled trial

Level of evidence: Level 2: Limited-quality, patient-oriented evidence

Strength of recommendation grade: Not applicable.

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