A late-stage intermediate in salinomycin biosynthesis is revealed by specific mutation in the biosynthetic gene cluster

Chembiochem. 2012 Jan 2;13(1):66-71. doi: 10.1002/cbic.201100590. Epub 2011 Nov 11.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosynthetic Pathways / genetics*
  • Genomic Library
  • Molecular Conformation
  • Mutation
  • Polyketide Synthases / genetics
  • Polyketide Synthases / metabolism*
  • Pyrans / chemistry
  • Pyrans / metabolism*
  • Streptomyces / enzymology
  • Streptomyces / genetics*
  • Streptomyces / metabolism

Substances

  • Pyrans
  • salinomycin
  • Polyketide Synthases