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Anaesthesia. 2011 Dec;66(12):1168-70. doi: 10.1111/j.1365-2044.2011.06895.x.

Treatment of cocaine overdose with lipid emulsion.

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John Hammond Department of Anaesthesia, East Surrey Hospital, Redhill, UK.


We describe the management and recovery of a 28-year-old man following a history of overdose by nasal inhalation of cocaine. The patient was presented in a comatose state suffering from seizures and marked cardiovascularly instability. Intravenous lipid emulsion was administered following initial resuscitation and tracheal intubation, as a means of treating persistent cardiac arrhythmias and profound hypotension. Following lipid emulsion therapy, the patient's life-threatening cardiovascular parameters rapidly improved and he recovered well without any side effects, thus being discharged within 2 days.

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