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Occup Med (Lond). 2012 Jan;62(1):64-6. doi: 10.1093/occmed/kqr172. Epub 2011 Nov 7.

Disulfiram reaction in an artist exposed to solvents.

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Centre for Occupational and Environmental Health Research, School of Public Health and Family Medicine, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa.


This case report describes an artist on treatment for alcoholism with disulfiram (Antabuse) who suffered chronic symptoms similar to those of a disulfiram alcohol reaction, which we attribute to his occupational exposure to products containing alcohol and other solvents. Symptoms abated with strict precautions to prevent exposure, although gradually returned over the course of months, causing him eventually to stop the medication. Medical practitioners should be aware of possible adverse interactions between occupational solvent exposures and disulfiram.

[Indexed for MEDLINE]

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