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Clin Geriatr Med. 2011 Nov;27(4):491-506. doi: 10.1016/j.cger.2011.07.001. Epub 2011 Sep 22.

Theories and mechanisms of aging.

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1
Department of Medicine, Louisiana State University Health Sciences Center, 1542 Tulane Avenue, New Orleans, LA 70113, USA. ccefal@lsuhsc.edu

Abstract

This article discusses various theories of aging and their relative plausibility related to the human aging process. Structural and physiologic changes of aging are discussed in detail by organ system. Each of the organ systems is discussed when applicable to the various theories of aging. Normal versus abnormal aging is discussed in the context of specific aging processes, with atypical presentations of disease and general links to life expectancy. Life expectancy and lifespan are discussed in the context of advances in medical science and the potential ultimate link to human life span.

PMID:
22062437
DOI:
10.1016/j.cger.2011.07.001
[Indexed for MEDLINE]
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