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Cell Metab. 2011 Nov 2;14(5):573-4. doi: 10.1016/j.cmet.2011.10.004.

Setting the tone: reactive oxygen species and the control of appetitive melanocortin neurons.

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1
Institute of Metabolic Sciences, Medical Research Laboratories, Department of Medicine, University of Cambridge, Cambridge, UK.

Abstract

The brain melanocortin system is a primary gateway through which energy balance is controlled. Diano and colleagues report a novel cellular mechanism mediated via reactive oxygen species (ROS) that regulates the activity of these melanocortin neurons in response to energy status, thereby modulating appetitive behavior (Diano et al., 2011).

PMID:
22055500
DOI:
10.1016/j.cmet.2011.10.004
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