Abstract
Synthesis and structural characterization of 3 sulfanilamido-1-phenylpyrazoles bearing on 1-phenyl group nitro substituent o-, m-, p-positioned are reported. All derivatives are analysed through 1H and 13C NMR spectroscopy. The MIC values obtained against Escherichia coli are briefly discussed in terms of structure-activity relationship.
MeSH terms
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Anti-Bacterial Agents / chemical synthesis*
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Escherichia coli / drug effects
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Nitro Compounds / chemical synthesis*
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Nitro Compounds / pharmacology
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Structure-Activity Relationship
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Sulfaphenazole / analogs & derivatives*
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Sulfaphenazole / chemical synthesis
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Sulfaphenazole / pharmacology
Substances
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Anti-Bacterial Agents
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Nitro Compounds
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Sulfaphenazole