Format

Send to

Choose Destination
See comment in PubMed Commons below
Hand Clin. 2011 Nov;27(4):467-79, ix. doi: 10.1016/j.hcl.2011.07.001.

Immunosuppressive protocols and immunological challenges related to hand transplantation.

Author information

1
Department of Surgery, Duke University, Durham, NC 27710, USA.

Abstract

There are many immunological challenges related to hand transplantation. Curbing the immune system's ability to effectively mount an immune response against the graft is the goal. As the various components of the immune response are defined and their mechanisms of action delineated, more specific immunosuppressive agents and protocols have been developed. Complications related to immunosuppression in hand transplant recipients are similar to incidences among solid organ recipients. With longer follow-up, the increased cardiovascular risk factors or the development of a neoplasm will likely cause mortality. Standardizing immunosuppression in hand transplantation with the long-term goal of minimization is critically needed.

PMID:
22051388
DOI:
10.1016/j.hcl.2011.07.001
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center