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World J Gastroenterol. 2011 Sep 21;17(35):4031-7. doi: 10.3748/wjg.v17.i35.4031.

Metabolic syndrome, lifestyle risk factors, and distal colon adenoma: a retrospective cohort study.

Author information

1
Department of Family Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 682-714, South Korea.

Abstract

AIM:

To investigate relationships between colorectal adenoma incidence, metabolic syndrome (MS) components and lifestyle factors.

METHODS:

We conducted a retrospective cohort study using data from individuals who had multiple sigmoidoscopies for colon cancer at the Health Promotion Center of Ulsan University Hospital in Korea from 1998 to 2007.

RESULTS:

By multivariate analysis, the incidence of distal colon adenoma was increased by more than 1.76 times in individuals with at least one component of MS compared to those without a component of MS. After adjustment for age, gender, smoking, drinking, and physical exercise, only high body mass index (BMI) was significantly associated with the incidence of distal colon adenoma (Hazard ratio 1.66, 95% confidence interval 1.05-2.62).

CONCLUSION:

Our results suggest that high BMI may increase the risk of colorectal adenoma in Korean adults.

KEYWORDS:

Body mass index; Distal colon adenoma; Korea; Lifestyle risk factor; Metabolic syndrome

PMID:
22046093
PMCID:
PMC3199563
DOI:
10.3748/wjg.v17.i35.4031
[Indexed for MEDLINE]
Free PMC Article
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