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Nutr Rev. 2011 Nov;69 Suppl 1:S43-8. doi: 10.1111/j.1753-4887.2011.00432.x.

Long-term brain and behavioral consequences of early iron deficiency.

Author information

1
Center for Neurobehavioral Development, University of Minnesota School of Medicine and College of Education and Human Development, Minneapolis, Minnesota 55455, USA. georg001@umn.edu

Abstract

Early iron deficiency not only affects brain and behavioral function during the period of iron deficiency, it persists long after treatment. The mechanisms include long-term alterations in dopamine metabolism, myelination, and hippocampal structure and function. Recent studies have demonstrated long-term genomic changes, which suggests the regulation of brain function is fundamentally altered.

PMID:
22043882
PMCID:
PMC3266848
DOI:
10.1111/j.1753-4887.2011.00432.x
[Indexed for MEDLINE]
Free PMC Article

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