Send to

Choose Destination
Behav Genet. 2012 May;42(3):345-53. doi: 10.1007/s10519-011-9516-8. Epub 2011 Oct 30.

Shared environmental contributions to substance use.

Author information

Department of Psychiatry, Virginia Institute for Psychiatric and Behavior Genetics, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298, USA.


The current study examined the association between substance use in the household during childhood, parental attitudes towards substance use and lifetime substance use in males. Subjects included 1081 monozygotic and 707 dizygotic twins from the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders. Retrospective reports of substance use and features of the family environment (adult household substance use and parental attitudes towards substance use) were obtained using a life history interview. A trivariate Cholesky decomposition was conducted using the program Mx to decompose common shared environmental variance. Findings suggest that family environmental factors accounted for a large proportion of the shared environmental effects for illicit drug use. Results illustrate an important way of extending behavior genetic research to reveal specific etiological environmental mechanisms.

[Indexed for MEDLINE]
Free PMC Article

Publication types, MeSH terms, Substance, Grant support

Publication types

MeSH terms


Grant support

Supplemental Content

Full text links

Icon for Springer Icon for PubMed Central
Loading ...
Support Center