Engineering aspects of biological ion channels--from biosensors to computational models for permeation

Protoplasma. 2012 Feb:249 Suppl 1:S3-9. doi: 10.1007/s00709-011-0333-y. Epub 2011 Oct 27.

Abstract

This paper presents two important engineering aspects of biological ion channels-how to build sensors out of gramicidin channels and how to construct computational models for ion channel permeation. We describe our recent research in these areas, potential challenges and possible solutions.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Transport
  • Biosensing Techniques / methods*
  • Computational Biology / methods*
  • Computer Simulation
  • Gramicidin / metabolism
  • Humans
  • Ion Channels / metabolism*
  • Models, Biological

Substances

  • Ion Channels
  • Gramicidin