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Stud Hist Philos Biol Biomed Sci. 2011 Dec;42(4):542-4. doi: 10.1016/j.shpsc.2011.07.001. Epub 2011 Jul 31.

Complex systems, evolution, and animal models.

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1
Americans For Medical Advancement, 2251 Refugio Rd, Goleta, CA 93117, USA. DrRayGreek@aol.com

Abstract

In this paper, we respond to arguments made concerning our position regarding animal models (Shelley, 2010) by briefly examining the fact that animals (human and nonhuman) are complex systems that have different evolutionary trajectories. This historical fact has implications for using animals as predictive models for human response to drugs and disease.

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PMID:
22035727
DOI:
10.1016/j.shpsc.2011.07.001
[Indexed for MEDLINE]
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