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Dialogues Clin Neurosci. 2011;13(3):346-51.

Post-traumatic stress disorder and declarative memory functioning: a review.

Author information

1
California School of Professional Psychology, Alliant International University, San Francisco, California, USA. ksamuelson@alliant.edu

Abstract

Declarative memory dysfunction is associated with post-traumatic stress disorder (PTSD). This paper reviews this literature and presents two frameworks to explain the nature of this dysfunction: that memory deficits are a product of neurobiological abnormalities caused by PTSD and/or that pre-existing memory deficits serve as a risk factor for the development of PTSD following trauma exposure. Brain regions implicated in declarative memory deficits include the hippocampus and prefrontal cortex, and imaging and biochemistry studies as they relate to memory dysfunction are described. Prospective and twin studies provide support for a risk factor model.

KEYWORDS:

PTSD; hippocampus; neuropsychology; trauma; verbal memory

PMID:
22033732
PMCID:
PMC3182004
[Indexed for MEDLINE]
Free PMC Article
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