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Biochem Biophys Res Commun. 1990 Aug 31;171(1):439-44.

Hydrolysis of synthetic chromogenic substrates by HIV-1 and HIV-2 proteinases.

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1
Department of Biochemistry, University of Wales College, Cardiff, U.K.

Abstract

Kinetic constants (Km,Kcat) are derived for the hydrolysis of a number of chromogenic peptide substrates by the aspartic proteinase from HIV-2. The effect of systematic replacement of the P2 residue on substrate hydrolysis by HIV-1 and HIV-2 proteinases is examined.

PMID:
2203349
[Indexed for MEDLINE]
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