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Med Clin North Am. 2011 Nov;95(6):1125-41. doi: 10.1016/j.mcna.2011.08.009.

Chronic obstructive pulmonary disease: a concise review.

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1
National Jewish Health, Pulmonary Division, Department of Medicine, Denver, CO 80206, USA. balkissoonr@NJHealth.org

Abstract

Globally, chronic obstructive pulmonary disease (COPD) is a major cause of significant morbidity and mortality, and is now the third leading cause of death in the United States. Over the past 15 years there has been a surge of bench and translational research regarding the genetics and pathogenesis of COPD, and several large-scale clinical trials have introduced new treatment paradigms for COPD. Current research also demonstrates that COPD is not just a lung disease and that there are several potential extrapulmonary manifestations and comorbidities that should be evaluated and treated when one identifies an individual as having COPD.

PMID:
22032431
DOI:
10.1016/j.mcna.2011.08.009
[Indexed for MEDLINE]
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